GWAS-LOCATE Brain Atlas

Predicted cell-type specificity of GWAS risk variants in the human brain, built on the Li et al. 2023 scATAC atlas.

GWAS-LOCATE method: predicting the cell type of action for GWAS SNPs. Three-panel diagram showing (i) a lead SNP and its LD block expanded to multiple candidate cell types, (ii) LD Summation calculated by adding peak signals across the LD block, and (iii) cell-type predictions derived from clustering the LD Summation matrix.

Genome build: hg38

Paste a list of rs-IDs, filter by trait, view the score heatmap.

All 42 scATAC tracks loaded on igv.js.

479

Traits

42

Cell types

23,494

Lead SNPs

1,016,013

Proxy SNPs